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Best Diaper Rash Cream for Babies Reviews 2022 – Top 5 Picks

If you want to make sure that your child gets the protection and relief he or she needs when it comes to skin irritation, you will need to look for the best diaper rash cream.

The cream that you choose will ultimately determine how effectively you are able to treat your child’s rash.

Without a doubt, a good diaper rash cream can help you to sooth your child’s irritated skin quickly when they get a rash, which is extremely important.

These creams will also allow you to prevent a rash from forming in the first place, thereby saving you and your child a lot of aggravation.

However, not all diaper rash creams are equal when it comes to sheer efficacy though, which is why you won’t want to purchase just any of them.

The best way to go about choosing the right cream to relieve and prevent diaper rash with your child is to learn all that you can about some of these products.

We have put together a list of the top 5 diaper rash creams on the market with detailed information about each one for your benefit.

Some of these creams have more powerful formulas than others, which is all the more reason to read the reviews listed below.

5 Best Diaper Rash Cream Reviews 2022

Aquaphor Baby Healing Ointment Advanced Therapy Skin Protectant is pediatrician recommended and clinically proven to restore smooth, healthy skin.

It is uniquely formulated with 41% petrolatum to allow oxygen to flow and help heal the skin.

This skin protection ointment also includes glycerin to moisturize, nourish and protect the skin to enhance healing.

If your baby’s skin is dry, chapped or irritated, this is definitely the best option you have.

There are many different ointment products on the market that are geared towards babies, but this one is certainly the best because of its unique formula and sheer effectiveness. It is great for dry and chapped skin.

If your baby has a drool rash, this ointment can be of great help.

Drool can create the sensitive areas around your baby’s mouth, chin and cheeks to become chafed quickly.

It is important that you have an ointment like this one for treating that sort of irritation.

Another great thing about this ointment is that it is perfect for dry hands and cuticles.

You will be able to use this ointment to take care of your own hands when they become dry.

The moisturizing glycerin in this ointment can provide you with the healing power you need to keep your hands smooth and soft.

It can also be useful when it comes to treating minor cuts and scrapes.

The ingredients in this ointment include petrolatum, panthenol and glycerin.

All of these ingredients have been proven to be very successful in treating rashes, cuts, scrapes, and mild skin irritation.


  • Versatile and unique formula that works on drool rash, diaper rash, dry hands, and minor cuts and scrapes.
  • Clinically proven to restore smooth, healthy skin.
  • Pediatrician recommended.


  • Doesn’t work well for more severe rashes.
  • May be a bit too oily or greasy for some babies and adults.

This rash ointment is pediatrician recommended and can effectively treat and help prevent diaper rash, so you can make sure it doesn’t become a problem in the first place.

It protects chafed skin due to diaper rash and helps seal out wetness before it becomes an issue.

A lot of parents love this ointment for a number of reasons, including the fact that it has a pleasant scent.

Boudraux’s Butt Paste Ointment consists of 16% zinc oxide, which makes it highly effective when it comes to fast diaper rash relief.

Zinc oxide is an FDA recognized ingredient proven to treat and help prevent diaper rash.

It contains more zinc oxide than Desitin Rapid Relief.

One of the great things about this diaper rash cream is that it has the thickest barrier of protection when compared to other leading zinc oxide diaper rash creams, such as A+D and Aquaphor.

Pediatricians recommend a thick skin barrier cream like Butt Paste for effective treatment of diaper rash.

There aren’t any harsh ingredients in this ointment at all, so you won’t have to worry about it actually irritating your baby’s skin.

It has a simple but effective formula that is made up of six different ingredients designed to be effective in treating and preventing diaper rash.

It was developed by a pharmacist and father of four.

It has a talc-free formula and is a great overall option for parents who want to make sure that their small child doesn’t develop diaper rash or gets the treatment they need for it.


  • Non-abrasive ingredients and a talc-free formula to ensure no irritation.
  • Effectively treats and prevents diaper rash from forming in the first place.
  • Recommended by pediatricians and developed by a pharmacist.


  • Can be a bit oily.
  • Some people may find the scent to be slightly unpleasant.

Available in a 16-oz container, Desitin Rapid Relief Diaper Rash Cream for Babies offers a fast-acting formula that helps to heal, soothe and treat diaper rash.

It has been rated as the #1 choice for pediatricians and moms.

Formulated for babies’ tender skin, it has been clinically shown to provide relief.

4 out of 5 parents agree that Desitin is strong enough for overnight protection, so you won’t have to worry about needing to get up in the middle of the night to do another application for your child’s rash.

This ointment can help to significant reduce redness and irritation of sensitive baby skin.

It also moisturizes the skin to sooth any chafing, which can be a significant cause of further irritation.

The activate ingredient in this product is zinc oxide, which can be found in most of these ointment products.

There are no dangerous or unsafe ingredients whatsoever, so you won’t have to worry about that at all.

Those who use this product on their baby will need to change wet or soiled diapers promptly, and cleanse the area thoroughly.

With a highly effective hypoallergenic design, it is no wonder why so many parents prefer this ointment compared to others.

If you are trying to find a great new ointment that will help keep rashes from developing on your child’s skin, it is important to look into this product.

There are many of these solutions available, but none that are quite as good as this one.


  • Formulated specifically for the sensitive skin of babies.
  • Natural formula with safe ingredients that won’t harm your child.
  • Clinically shown to provide relief for babies with a rash.


  • Has parabans in it.
  • Can be a little bit messy.

The Wleda Calendula Baby Diaper Rash Cream is Europe’s #1 rated natural baby diaper rash cream.

It has a completely natural, organic formula with calandeula extract from flowers grown in Weleda’s own biodynamic gardens in Germany.

It is free of any preservatives, fragrances and petroleum-derived material.

Another great thing about this diaper rash crash is that it creates a thick soothing barrier formulated with pharmaceutical-grade zinc oxide.

Weleda fair trade beeswax provides a breathable layer of protection to your baby’s bottom.

If you are looking for a great new ointment to use for diaper rash, this one is highly recommended overall.

This rich cream cares for delicate skin in the diaper area by protecting from moisture.

The zinc oxide forms a protective barrier against excessive wetness while organic calendula extract is blended with sweet almond oil and sesame oil to be nourishing and gentle to your baby’s bottom.

The organic anti-inflammatory calendula extract comes from flowers grown in biodynamic gardens in Germany.

Instead of mineral oil found in most diaper rash creams, Weleda uses fair trade beeswax, which provides a breathable layer of protection for your baby’s skin.

It is completely dermatologist-tested and safe for most baby skin, even sensitive.

It is not tested on animals and is free of synthetic preservatives and fragrances.

When it comes to getting the best diaper rash cream for your child, you will definitely be glad you took a close look at this one.

With lots of positive customer reviews, this cream is a great choice for any parent who wants to protect their baby’s skin effectively.


  • Natural and organic formula with no preservatives or fragrances.
  • Powerful anti-inflammatory properties.
  • Creates a thick soothing barrier that protects against diaper rash.


  • Some babies and adults may be sensitive to the odor.
  • Can be a bit oily.

The CeraVe Baby Diaper Rash Cream comes in a 3-ounce bottle and has a unique fragrance-free and non-greasy formula that absorbs quickly so no mess is left behind.

Ceramides in this ointment help repair the skin barrier. It has a hypoallergenic formula, so it is great even for those with sensitive skin and allergies.

This ointment is completely free of all parabens, sulfates and phthalates.

You can use this diaper rash cream to restore your baby’s skin and keep it healthy over the years.

The patented formula with essential ceramides (ceramide 3, ceramide 6-II and ceramide 1) and invisible zinc glides leave a protect barrier that seals out wetness without producing a thick sticky mess.

The natural ingredients that this cream is made up of are very powerful when it comes to treating and preventing diaper rash.

This means that you will have a very effective way to prevent this problem from occurring with your child in the first place.

If you want to take good care of your baby’s skin, it is highly recommended that you take the time to see what this product has to offer.

There are a lot of positive reviews for this diaper rash ointment, and it is definitely one of the more powerful naturally formulated options on the market right now.

The InvisibleZinc is one of the main reasons that this ointment works so well.

If you are currently looking for an ointment that can protect your child’s skin from irritating rashes, this CeraVe ointment is an excellent selection to consider.


  • Hypoallergenic design that is appropriate even for sensitive skin.
  • Free of parabens, sulfates and phthalates.
  • Ceramides help repair the skin barrier for maximum effectiveness.


  • Some people are sensitive to the smell of this ointment.
  • Sometimes the pump nozzle gets plugged up.


There are many different ointments that exist for treating diaper rashes or eczema. That being said, you will have to take a closer look at ingredients and brands of the ointment because it might affect severely to their skin.

A lot of people rush into a final decision without doing all the necessary research, which is a big mistake.

Aquaphor Baby Healing Ointment Advanced Therapy Skin Protectant - Editor's Choice

If you are looking for the very best diaper rash cream for your child, the Aquaphor Baby Advanced Therapy Healing Ointment is definitely the one to buy. This particular ointment has been proven to be the most effective in clinical trials.

Product Brand: Aquaphor

Product Currency: USD

Product In-Stock: InStock

Editor's Rating: